产品详情
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量48kDa；实际分子量44kDa/48kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 5599 |
Swiss Prot | P45983 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | Cytoplasm, Nucleus. |
Applications（应用）
Species reactivity（反应种属）
Human Mouse Rat
Tested Applications（已测试应用）
WB IHC-P IF-P ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:1000 - 1:10000 |
IHC-P | 1:50 - 1:100 |
IF-P | 1:50 - 1:100 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes a member of the MAP kinase family. MAP kinases integrate diverse biochemical signals and participate in many cellular events including proliferation, differentiation, transcriptional regulation and development. This kinase can be activated by various cellular stimuli and targets specific transcription factors to mediate immediate-early gene expression. Its activation by TNF-α is necessary for TNF-α-triggered apoptosis, and it also participates in UV-induced apoptosis via the cytochrome c-dependent cell death pathway. Studies on the mouse homolog indicate its critical roles in T-cell proliferation, apoptosis and differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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