产品详情
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量48kDa/52kDa； 实际分子量46kDa/54kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 5599/5601/5602 |
Swiss Prot | P45983/P45984/P53779 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | axon, basal dendrite, cytoplasm, cytosol, mitochondrion, nucleoplasm, nucleus, synapse. |
Applications（应用）
Species reactivity（反应种属）
Human Mouse Rat
Tested Applications（已测试应用）
WB IHC-P IF-P ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:1000-1:2500 |
IHC-P | 1:50-1:100 |
IF-P | 1:50-1:100 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes a member of the MAP kinase family. MAP kinases integrate diverse biochemical signals and regulate a broad range of cellular processes, including proliferation, differentiation, transcription and development. Activated by various cellular stimuli, this kinase targets specific transcription factors to mediate immediate-early gene expression. Its activation by TNF-α is essential for TNF-α-induced apoptosis, and it also participates in UV-triggered apoptosis through the cytochrome c-mediated cell death pathway. Research on the mouse homolog demonstrates its pivotal function in T-cell proliferation, apoptosis and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
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