产品详情
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量34kDa；实际分子量38kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 1398 |
Swiss Prot | P46108 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | Cell membrane, Cytoplasm. |
Applications（应用）
Species reactivity（反应种属）
Human
Tested Applications（已测试应用）
WB ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:1000-1:2500 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes an adaptor protein that interacts with multiple tyrosine-phosphorylated proteins. It contains several SH2 and SH3 src-homology domains and participates in multiple signaling cascades. Through SH2-phosphotyrosine binding, it recruits cytoplasmic proteins near tyrosine kinases. Its N-terminal SH2 domain promotes cell transformation, while the C-terminal SH3 domain suppresses this process. Two alternative transcripts produce isoforms with distinct biological functions.
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