产品详情
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量59kDa；实际分子量68kDa/75kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 6198 |
Swiss Prot | P23443 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | Cell junction, Cytoplasm, Mitochondrion outer membrane, Mitochondrion, Nucleus, synapse, synaptosome. |
Applications（应用）
Species reactivity（反应种属）
Human Mouse Rat
Tested Applications（已测试应用）
WB IF/ICC ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:1000-1:2000 |
IF/ICC | 1:100-1:1000 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes a serine/threonine kinase belonging to the ribosomal S6 kinase family. The protein responds to mTOR signaling to drive protein synthesis, cell growth and proliferation. Its dysregulated activity is linked to human cancers. Alternative splicing generates multiple transcript variants. Different translation initiation sites produce isoforms with varying N-terminal lengths, which may exhibit distinct subcellular localization. Two pseudogenes of this gene are found on chromosome 17.
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