产品详情
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量149kDa；实际分子量150kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 57521 |
Swiss Prot | Q8N122 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | Cytoplasm, Cytoplasmic granule, Lysosome, Cytoplasmic granule, Lysosome. |
Applications（应用）
Species reactivity（反应种属）
Human
Tested Applications（已测试应用）
WB ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:2500-1:10000 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000),a sequential dilution method is strongly recommended to ensure measurement accuracy. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes a component of the signaling pathway that modulates cell growth according to nutrient and insulin status. The protein forms a stoichiometric complex with mTOR kinase and also interacts with 4E-BP1 and ribosomal S6 kinase. It exerts positive regulation on downstream S6 kinase and suppresses mTOR activity. Several transcript variants encoding distinct isoforms of this gene have been identified.
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