产品详情
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量13kDa；实际分子量15-20kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 1978 |
Swiss Prot | Q13541 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | Cytoplasm, Cytosol. |
Applications（应用）
Species reactivity（反应种属）
Human Mouse
Tested Applications（已测试应用）
WB ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:1000-1:2000 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes a translational repressor. It directly binds eukaryotic translation initiation factor 4E (eIF4E), a rate-limiting subunit of the complex responsible for recruiting 40S ribosomal subunits to the 5' terminus of mRNA. Binding to eIF4E blocks complex formation and suppresses translation. Phosphorylation triggered by stimuli such as UV irradiation and insulin signaling causes its dissociation from eIF4E, thereby activating mRNA translation.
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