产品详情
Isotype(亚型) | IgG |
Calculated MW(分子量) | 理论分子量13kDa;实际分子量15-20kDa |
Immunogen(免疫原) | Recombinant protein (or fragment). |
Gene ID | 1978 |
Swiss Prot | Q13541 |
Purification Method(纯化方式) | Affinity purification |
Subcellular location(亚细胞定位) | cytoplasm, cytosol. |
Applications(应用)
Species reactivity(反应种属)
Human Mouse
Tested Applications(已测试应用)
WB ELISA
Recommended Dilutions(推荐稀释比例)
Tested Applications | Recommended Dilutions |
WB | 1:1000-1:6000 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage(储存)
Storage Buffer(储存缓冲液)
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction(储存条件)
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information(背景信息)
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
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