服务介绍
Isotype（亚型） | IgG |
Calculated MW（分子量） | 理论分子量41kDa；实际分子量40kDa |
Immunogen（免疫原） | Recombinant protein (or fragment). |
Gene ID | 1432 |
Swiss Prot | Q16539 |
Purification Method（纯化方式） | Affinity purification |
Subcellular location（亚细胞定位） | Cytoplasm, Nucleus. |
Applications（应用）
Species reactivity（反应种属）
Human Mouse Rat
Tested Applications（已测试应用）
WB IHC-P ELISA
Recommended Dilutions（推荐稀释比例）
Tested Applications | Recommended Dilutions |
WB | 1:500-1:1000 |
IHC-P | 1:50-1:200 |
ELISA | Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Storage（储存）
Storage Buffer（储存缓冲液）
PBS with 0.09% sodium azide,0.05%BSA,50% glycerol,pH7.3.
Storage Instruction（储存条件）
Shiped at 4℃.Short term 4℃(1-2weeks).It isrecommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Background Information（背景信息）
This gene encodes a member of the MAP kinase family. MAP kinases serve as hubs for diverse biochemical signals and take part in numerous cellular events, including proliferation, differentiation, transcriptional regulation and development. This kinase can be activated by various environmental stresses and proinflammatory cytokines. Activation occurs through phosphorylation by MAP kinase kinases (MKKs), or autophosphorylation induced by interaction with MAP3K7IP1/TAB1. Its substrates comprise transcription regulators ATF2, MEF2C and MAX, cell cycle regulator CDC25B, and tumor suppressor p53. These findings indicate its functions in stress-related transcription, cell cycle control and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been identified.
相关服务产品
欢迎您的产品咨询
